Meet Cathy Tie, Bride of “China’s Frankenstein”
Since the Chinese biophysicist He Jiankui was released from prison in 2022, he has sought to make a scientific comeback and to repair his reputation after a three-year incarceration for illegally creating the world’s first gene-edited children. While he has bounced between cities, jobs, and meetings with investors, one area of visible success on his comeback trail has been his X.com account, @Jiankui_He, which has become his main way of spreading his ideas to the world. Starting in September 2022, when he joined the platform, the account stuck to the scientist’s main themes, including promising a more careful approach to his dream of creating more gene-edited children. “I will do it, only after society has accepted it,” he posted in August 2024. He also shared mundane images of his daily life, including golf games and his family. But over time, it evolved and started to go viral. First came a series of selfies accompanied by grandiose statements (“Every pioneer or prophet must suffer”). Then, in April of this year, it became particularly outrageous and even troll-like, blasting out bizarre messages (“Good morning bitches. How many embryos have you gene edited today?”). This has left observers unsure what to take seriously. Last month, in reply to MIT Technology Review’s questions about who was responsible for the account’s transformation into a font of clever memes, He emailed us back: “It’s thanks to Cathy Tie.” You may not be familiar with Tie, but she’s no stranger to the public spotlight. A former Thiel fellow, she is a partner in the attention-grabbing Los Angeles Project, which promised to create glow-in-the-dark pets. Over the past several weeks, though, the 29-year-old Canadian entrepreneur has started to get more and more attention as the new wife to (and apparent social media mastermind behind) He Jiankui. On April 15, He announced a new venture, Cathy Medicine, that would take up his mission of editing human embryos to create people resistant to diseases like Alzheimer’s or cancer. Just a few days later, on April 18, He and Tie announced that they had married, posting pictures of themselves in traditional Chinese wedding attire. But now Tie says that just a month after she married “the most controversial scientist in the world,” her plans to relocate from Los Angeles to Beijing to be with He are in disarray; she says she’s been denied entry to China and the two “may never see each other again,” as He’s passport is being held by Chinese authorities and he can’t leave the country. Reached by phone in Manila, Tie said authorities in the Philippines had intercepted her during a layover on May 17 and told her she couldn’t board a plane to China, where she was born and where she says she has a valid 10-year visa. She claims they didn’t say why but told her she is likely “on a watch list.” (MIT Technology Review could not independently confirm Tie’s account.) “While I’m concerned about my marriage, I am more concerned about what this means for humanity and the future of science,” Tie posted to her own X account. A match made in gene-editing heaven The romance between He and Tie has been playing out in public over the past several weeks through a series of reveals on He’s X feed, which had already started going viral late last year thanks to his style of posting awkward selfies alongside maxims about the untapped potential of heritable gene editing, which involves changing people’s DNA when they’re just embryos in an IVF dish. “Human [sic] will no longer be controlled by Darwin’s evolution,” He wrote in March. That post, which showed him standing in an empty lab, gazing into the distance, garnered 9.7 million views. And then, a week later, he collected 13.3 million for this one: “Ethics is holding back scientific innovation and progress.” In April, the feed started to change even more drastically. He’s posts became increasingly provocative, with better English and a unique sensibility reflecting online culture. “Stop asking for cat girls. I’m trying to cure disease,” the account posted on April 15. Two days later, it followed up: “I literally went to prison for this shit.” This shift coincided with the development of his romance with Tie. Tie told us she has visited China three times this year, including a three-week stint in April when she and He got married after a whirlwind romance. She bought him a silver wedding ring made up of intertwined DNA strands. The odd behavior on He’s X feed and the sudden marriage have left followers wondering if they are watching a love story, a new kind of business venture, or performance art. It might be all three. A wedding photo posted by Tie on the Chinese social media platform Rednote shows the couple sitting at a table in a banquet hall, with a small number of guests. MIT Technology Review has been able to identify several people who attended: Cai Xilei, He’s criminal attorney; Liu Haiyan, an investor and former business partner of He; and Darren Zhu, an artist and Thiel fellow who is making a “speculative” documentary about the biophysicist that will blur the boundaries of fiction and reality. In the phone interview, Tie declined to say if she and He are legally married. She also confirmed she celebrated a wedding less than one year ago with someone else in California, in July of 2024, but said they broke up after a few months; she also declined to describe the legal status of that marriage. In the phone call, Tie emphasized that her relationship with He is genuine: “I wouldn’t marry him if I wasn’t in love with him.” An up-and-comer Years before Tie got into a relationship with He, she was getting plenty of attention in her own right. She became a Thiel fellow in 2015, when she was just 18. That program, started by the billionaire Peter Thiel, gave her a grant of $100,000 to drop out of the University of
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