{"id":121907,"date":"2026-10-03T03:01:57","date_gmt":"2026-10-03T03:01:57","guid":{"rendered":"https:\/\/youzum.net\/a-new-contest-pits-competitors-against-each-other-in-a-race-to-biological-youth\/"},"modified":"2026-10-03T03:01:57","modified_gmt":"2026-10-03T03:01:57","slug":"a-new-contest-pits-competitors-against-each-other-in-a-race-to-biological-youth","status":"publish","type":"post","link":"https:\/\/youzum.net\/es\/a-new-contest-pits-competitors-against-each-other-in-a-race-to-biological-youth\/","title":{"rendered":"A new contest pits competitors against each other in a race to biological youth"},"content":{"rendered":"<div data-chronoton-summary=\"&lt;ul&gt;&lt;br&gt;&lt;li&gt;&lt;strong&gt;Biological age as a competition:&lt;\/strong&gt; A new six-month contest called pits around 500 participants against each other to reverse their biological age, using tools like epigenetic blood tests, brain scans, face-aging apps, and grip strength measurements.&lt;\/li&gt;&lt;br&gt;&lt;li&gt;&lt;strong&gt;The science is promising but imperfect:&lt;\/strong&gt; Over 100 biological &quot;aging clocks&quot; exist, but experts caution they aren't yet reliable enough for individual use\u2014nobody fully understands what each one actually measures.&lt;\/li&gt;&lt;br&gt;&lt;li&gt;&lt;strong&gt;Data collection is a goal:&lt;\/strong&gt; Founder Christin Glorioso hopes the contest generates the world's most comprehensive aging-clock dataset, while also giving longevity companies a cheaper alternative to running formal clinical trials.&lt;\/li&gt;&lt;br&gt;&lt;li&gt;&lt;strong&gt;The leaderboard is shaping up:&lt;\/strong&gt; One competitor's biological age clocks in nearly 29 years below their chronological age\u2014while another 47-year-old received a biological age of 100 based on how slowly she rises from a chair&lt;\/li&gt;&lt;\/ul&gt;\" data-chronoton-post-id=\"1145610\" data-chronoton-expand-collapse=\"1\" data-chronoton-analytics-enabled=\"1\"><\/div>\n<p>This week, I officially signed up for an unusual competition. One that rewards competitors for getting <em>younger<\/em>.<\/p>\n<p>I recently turned 40, and I don\u2019t need reminding that both time and my chronological age only tick forward. But this game is focused on competitors\u2019 <em>biological<\/em> ages\u2014figures that are meant to provide a better way to measure the age-related health of our organs and bodies.<\/p>\n<p>Over a six-month period, around 500 of us will try to reverse our biological age as measured in a bunch of different ways. There\u2019s even a leaderboard! The winners will include the person who shows the greatest difference between their chronological and biological age, as well as the person who manages to reverse their biological age the most.<\/p>\n<p><strong>The competition is the brainchild of the neuroscientist and physician Christin Glorioso,<\/strong> who is also founder and CEO of NeuroAge Therapeutics. The company offers tools to track brain health and aging and is\u00a0<a href=\"https:\/\/www.neuroagetx.com\/our-science\">running a trial<\/a> to find out if biological brain age can predict the onset of Alzheimer\u2019s disease.<\/p>\n<p>Glorioso says she has several goals for <a href=\"https:\/\/www.neuroagetx.com\/events\/younger\">the Younger contest<\/a>. The first, she tells me, is to \u201cexplain to the world what <a href=\"https:\/\/www.technologyreview.com\/2022\/04\/15\/1050019\/aging-clocks\/?utm_source=the_checkup&amp;utm_medium=email&amp;utm_campaign=the_checkup.unpaid.engagement&amp;utm_content=10-01-26\">aging clocks<\/a> are.\u201d Regular Checkup readers will be familiar with these tools, but for the uninitiated, they are basically designed to measure biological age.<\/p>\n<p>Many measure chemical signatures that form a layer on top of our DNA and seem to change with age. But others might involve looking at proteins or lipids in blood. Some are designed to measure functional health, while others predict when a person will die. There are more than a hundred clocks out there, and they probably each capture a specific aspect of the biological process of aging.<\/p>\n<p>These clocks are proving <a href=\"https:\/\/www.technologyreview.com\/2025\/10\/14\/1124977\/aging-clocks-biology-mortality-longevity\/?utm_source=the_checkup&amp;utm_medium=email&amp;utm_campaign=the_checkup.unpaid.engagement&amp;utm_content=10-01-26\">very useful for scientists<\/a>, who use them to study aging and development in humans and many other species. But using them to estimate the biological age of an individual person is more controversial. They\u2019re just not good enough for that yet.<\/p>\n<p><strong>Part of the problem is that we don\u2019t really understand what each clock is capturing. <\/strong>Glorioso hopes that data collected through the Younger contest might help answer that question. She\u2019s hoping to generate \u201cthe world\u2019s most comprehensive clock dataset.\u201d<\/p>\n<p>Some <a href=\"https:\/\/www.technologyreview.com\/2024\/03\/18\/1089888\/the-quest-to-legitimize-longevity-medicine\/?utm_source=the_checkup&amp;utm_medium=email&amp;utm_campaign=the_checkup.unpaid.engagement&amp;utm_content=10-01-26\">longevity clinics<\/a> try to get around the limits of biological age testing by using multiple clocks. That\u2019s this competition\u2019s approach too. As a standard competitor, I\u2019ll be sending a blood spot sample to TruDiagnostic, a company that measures epigenetic chemical groups on DNA and offers to reveal an overall biological age as well as a person\u2019s pace of aging and the biological ages of each of 11 organ systems, including the heart and brain.<\/p>\n<p>I\u2019ll get a brain age score from NeuroAge once I complete the cognitive tasks on offer. I\u2019ll also submit some physical measures like grip strength. And I\u2019ll upload a series of selfies to an app developed by a team at Harvard that promises to tell me my face age. That\u2019s exactly what it sounds like\u2014an estimate of how old my face looks.<\/p>\n<p>I\u2019m intrigued to see my scores, even though I know I shouldn\u2019t put too much stock in them. The first time I took a test, four years ago, the company I used <a href=\"https:\/\/www.technologyreview.com\/2022\/11\/18\/1063466\/i-found-out-biological-age\/?utm_source=the_checkup&amp;utm_medium=email&amp;utm_campaign=the_checkup.unpaid.engagement&amp;utm_content=10-01-26\">gave me a biological age<\/a> that matched my chronological age, which was a little disappointing and, if I\u2019m honest, a bit underwhelming. A year later, the same company <a href=\"https:\/\/www.technologyreview.com\/2022\/11\/18\/1063466\/i-found-out-biological-age\/?utm_source=the_checkup&amp;utm_medium=email&amp;utm_campaign=the_checkup.unpaid.engagement&amp;utm_content=10-01-26\">told me I had a young heart<\/a> but a relatively old brain, liver, and hormonal system. My lifestyle hasn\u2019t changed much since then. Will the years have made much difference?<\/p>\n<p>(Ultra competitors\u2014who pay $4,499 rather than the $999 cost of regular entry\u2014are also offered a range of other blood tests and clocks, as well as MRI and DEXA scans. I\u2019ve got complimentary press access to the standard package.)<\/p>\n<p><strong>Glorioso is also hoping to gather information about the effects of some purported longevity approaches. <\/strong>During the competition, some participants will be offered red-light masks, access to a sauna, or other low-risk offerings that partner companies who are sponsoring the event to varying degrees might want to collect data on. \u201cA lot of these companies just can\u2019t afford to run [clinical] trials,\u201d says Glorioso.<\/p>\n<p>She also sees the event as a public health initiative. A couple of years ago, David Sinclair, who studies aging at Harvard Medical School, and his colleagues estimated that if we could slow down aging in the general population and increase life expectancy by one year, it <a href=\"https:\/\/www.nature.com\/articles\/s43587-021-00080-0\">would save the US economy $38 trillion<\/a>.<\/p>\n<p>The event officially kicks off in January, but around 120 people have already signed up, says Glorioso. Ultimately, she expects 500 participants. Each person\u2019s six-month run starts as soon as they take their baseline measurements, whenever that may be. A handful of people have already started. \u201cI think the majority of people are going to want to sign up after the holidays,\u201d says Glorioso. \u201cThey\u2019re not going to want to be trying to win an aging contest over Christmas and Hanukkah.\u201d<\/p>\n<p>Glorioso took her own baseline measurements back in August. Those initial tests suggested that her biological age was around 10 years below her chronological age. That sounded pretty impressive to me until I looked at the leaderboard and saw that competitor @Fred had a biological age 28.8 years below his chronological age.<\/p>\n<p><strong>The leaderboard is pretty sparse at the moment,<\/strong> as only seven people have logged their baseline measurements so far. Six of them have biological ages tracking low, but one 47-year-old has been given a biological age of 68.1. She\u2019s competing publicly, so I can see the breakdown of her scores. The worst is for the speed at which she can stand from sitting in a chair\u2014by that measure, she\u2019s been given a biological age of 100.<\/p>\n<p>Hillary Lin, a longevity-focused physician in New York, has just started logging her baseline measurements for the competition. She tells me she\u2019s taken biological age tests in the past and that they\u2019ve tended to give scores below her chronological age, which is currently 37. Last year, the TruDiagnostic test put her pace of aging at 0.75\u2014suggesting she\u2019s only doing nine months\u2019 worth of aging in a typical year. \u201cThat\u2019s supposed to be quite good,\u201d she says.<\/p>\n<p>If it had been up to her, Lin says, she would have incorporated more blood tests into the competition, to build a fuller picture of a person\u2019s health. And she\u2019s worried that a six-month period might not be long enough to see changes in biological measures of aging. Still, she\u2019s excited, and is already making plans to improve her sleep, diet, and exercise.<\/p>\n<p>But she already follows a high-protein, low-carb diet and works out at the gym every day. She also visits a sauna every few days (sauna use <a href=\"https:\/\/lifestylemedicine.stanford.edu\/sauna-use-as-a-lifestyle-practice\/\">has been linked to improved heart health<\/a>). Glorioso\u2019s efforts are impressive too. She tells me she\u2019s started drinking a smoothie made from\u00a0<a href=\"https:\/\/www.neuroagetx.com\/blog\/the-duckweed-smoothie-behind-the\">a pond plant that has been linked to health improvements<\/a>, and that she\u2019s cut added sugar and deep-fried foods from her diet. She\u2019s also bought \u201ca bunch of fancy Korean sunscreens\u201d in an attempt to lower her face age.<\/p>\n<p>I haven\u2019t received my kit or logged my baseline measurements yet, and I\u2019ll wait until then to start setting health goals. I don\u2019t fancy my chances against these two competitors. But at the very least, I hope I can stand up faster than a 100-year-old.<\/p>\n<p><em>This article first appeared in The Checkup,\u00a0<\/em>MIT Technology Review\u2019s<em>\u00a0weekly biotech newsletter. To receive it in your inbox every Thursday, and read articles like this first,\u00a0<\/em><a href=\"https:\/\/forms.technologyreview.com\/newsletters\/biotech-the-checkup\/?_ga=2.241810882.15113993.1664981064-43237434.1647441349\"><em>sign up here<\/em><\/a>.<\/p>","protected":false},"excerpt":{"rendered":"<p>This week, I officially signed up for an unusual competition. One that rewards competitors for getting younger. I recently turned 40, and I don\u2019t need reminding that both time and my chronological age only tick forward. But this game is focused on competitors\u2019 biological ages\u2014figures that are meant to provide a better way to measure the age-related health of our organs and bodies. Over a six-month period, around 500 of us will try to reverse our biological age as measured in a bunch of different ways. There\u2019s even a leaderboard! The winners will include the person who shows the greatest difference between their chronological and biological age, as well as the person who manages to reverse their biological age the most. The competition is the brainchild of the neuroscientist and physician Christin Glorioso, who is also founder and CEO of NeuroAge Therapeutics. The company offers tools to track brain health and aging and is\u00a0running a trial to find out if biological brain age can predict the onset of Alzheimer\u2019s disease. Glorioso says she has several goals for the Younger contest. The first, she tells me, is to \u201cexplain to the world what aging clocks are.\u201d Regular Checkup readers will be familiar with these tools, but for the uninitiated, they are basically designed to measure biological age. Many measure chemical signatures that form a layer on top of our DNA and seem to change with age. But others might involve looking at proteins or lipids in blood. Some are designed to measure functional health, while others predict when a person will die. There are more than a hundred clocks out there, and they probably each capture a specific aspect of the biological process of aging. These clocks are proving very useful for scientists, who use them to study aging and development in humans and many other species. But using them to estimate the biological age of an individual person is more controversial. They\u2019re just not good enough for that yet. Part of the problem is that we don\u2019t really understand what each clock is capturing. Glorioso hopes that data collected through the Younger contest might help answer that question. She\u2019s hoping to generate \u201cthe world\u2019s most comprehensive clock dataset.\u201d Some longevity clinics try to get around the limits of biological age testing by using multiple clocks. That\u2019s this competition\u2019s approach too. As a standard competitor, I\u2019ll be sending a blood spot sample to TruDiagnostic, a company that measures epigenetic chemical groups on DNA and offers to reveal an overall biological age as well as a person\u2019s pace of aging and the biological ages of each of 11 organ systems, including the heart and brain. I\u2019ll get a brain age score from NeuroAge once I complete the cognitive tasks on offer. I\u2019ll also submit some physical measures like grip strength. And I\u2019ll upload a series of selfies to an app developed by a team at Harvard that promises to tell me my face age. That\u2019s exactly what it sounds like\u2014an estimate of how old my face looks. I\u2019m intrigued to see my scores, even though I know I shouldn\u2019t put too much stock in them. The first time I took a test, four years ago, the company I used gave me a biological age that matched my chronological age, which was a little disappointing and, if I\u2019m honest, a bit underwhelming. A year later, the same company told me I had a young heart but a relatively old brain, liver, and hormonal system. My lifestyle hasn\u2019t changed much since then. Will the years have made much difference? (Ultra competitors\u2014who pay $4,499 rather than the $999 cost of regular entry\u2014are also offered a range of other blood tests and clocks, as well as MRI and DEXA scans. I\u2019ve got complimentary press access to the standard package.) Glorioso is also hoping to gather information about the effects of some purported longevity approaches. During the competition, some participants will be offered red-light masks, access to a sauna, or other low-risk offerings that partner companies who are sponsoring the event to varying degrees might want to collect data on. \u201cA lot of these companies just can\u2019t afford to run [clinical] trials,\u201d says Glorioso. She also sees the event as a public health initiative. A couple of years ago, David Sinclair, who studies aging at Harvard Medical School, and his colleagues estimated that if we could slow down aging in the general population and increase life expectancy by one year, it would save the US economy $38 trillion. The event officially kicks off in January, but around 120 people have already signed up, says Glorioso. Ultimately, she expects 500 participants. Each person\u2019s six-month run starts as soon as they take their baseline measurements, whenever that may be. A handful of people have already started. \u201cI think the majority of people are going to want to sign up after the holidays,\u201d says Glorioso. \u201cThey\u2019re not going to want to be trying to win an aging contest over Christmas and Hanukkah.\u201d Glorioso took her own baseline measurements back in August. Those initial tests suggested that her biological age was around 10 years below her chronological age. That sounded pretty impressive to me until I looked at the leaderboard and saw that competitor @Fred had a biological age 28.8 years below his chronological age. The leaderboard is pretty sparse at the moment, as only seven people have logged their baseline measurements so far. Six of them have biological ages tracking low, but one 47-year-old has been given a biological age of 68.1. She\u2019s competing publicly, so I can see the breakdown of her scores. The worst is for the speed at which she can stand from sitting in a chair\u2014by that measure, she\u2019s been given a biological age of 100. Hillary Lin, a longevity-focused physician in New York, has just started logging her baseline measurements for the competition. She tells me she\u2019s taken biological age tests in the past and that they\u2019ve tended to give scores below her chronological<\/p>","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"_pvb_checkbox_block_on_post":false,"footnotes":""},"categories":[52,5,7,1],"tags":[],"class_list":["post-121907","post","type-post","status-publish","format-standard","hentry","category-ai-club","category-committee","category-news","category-uncategorized","pmpro-has-access"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.3 - 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One that rewards competitors for getting younger. I recently turned 40, and I don\u2019t need reminding that both time and my chronological age only tick forward. But this game is focused on competitors\u2019 biological ages\u2014figures that are meant to provide a better way to measure&hellip;","_links":{"self":[{"href":"https:\/\/youzum.net\/es\/wp-json\/wp\/v2\/posts\/121907","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/youzum.net\/es\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/youzum.net\/es\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/youzum.net\/es\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/youzum.net\/es\/wp-json\/wp\/v2\/comments?post=121907"}],"version-history":[{"count":0,"href":"https:\/\/youzum.net\/es\/wp-json\/wp\/v2\/posts\/121907\/revisions"}],"wp:attachment":[{"href":"https:\/\/youzum.net\/es\/wp-json\/wp\/v2\/media?parent=121907"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/youzum.net\/es\/wp-json\/wp\/v2\/categories?post=121907"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/youzum.net\/es\/wp-json\/wp\/v2\/tags?post=121907"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}